Author

Minshan Lin

Case Western Reserve University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Polyxeni PhilippidouiD· 4 shared Alicia N. VagnozziiD· 3 shared Matthew T. Moore· 3 shared Aambar Agarwal· 2 shared Elyse M. Brozost· 2 shared Lindsay A. SchwarziD· 2 shared Lucie JeannotteiD· 2 shared Raquel López de BoeriD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Polyxeni PhilippidouORCID

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Author profile →

4 papers

Recent·Most cited

A cholinergic spinal pathway for the adaptive control of breathing

Minshan Lin, Giulia Benedetta Calabrese, Anthony V. Incognito, Matthew T. Moore, Aambar Agarwal, Richard J. A. Wilson, Laskaro Zagoraiou, Simon A. Sharples, Gareth Brian Miles, Polyxeni Philippidou

This study identifies a spinal cholinergic pathway that enhances breathing by amplifying phrenic motor neuron output during hypercapnia.

Cell Reports · Aug 1, 2025Peer-reviewedNeuroscience

A sustained Hox program delineates brainstem neurons essential for breathing

Matthew T. Moore, Minshan Lin, Alicia N. Vagnozzi, Raquel López de Boer, Elyse M. Brozost, Lucie Jeannotte, Lindsay A. Schwarz, Polyxeni Philippidou

The paper identifies Hox5's role in organizing and specializing brainstem neurons critical for breathing, showing its necessity for respiratory function and survival.

bioRxiv · Aug 1, 2025 · PreprintNeuroscience

Multimodal Hox5 activity generates motor neuron diversity

Ritesh KC, Raquel López de Boer, Minshan Lin, Alicia N. Vagnozzi, Lucie Jeannotte, Polyxeni Philippidou

This study identifies how Hoxa5 interacts with transcription factors and regulates chromatin accessibility to generate motor neuron subtype diversity in mice.

Communications Biology · Sep 17, 2024Peer-reviewedDevelopmental Biology

Coordinated cadherin functions sculpt respiratory motor circuit connectivity

Alicia N. Vagnozzi, Matthew T. Moore, Minshan Lin, Elyse M. Brozost, Ritesh KC, Aambar Agarwal, Lindsay A. Schwarz, Xin Duan, Niccolò Zampieri, Lynn T. Landmesser, Polyxeni Philippidou

This study shows that coordinated cadherin activity in respiratory motor neurons and interneurons is essential for proper circuit connectivity and breathing function.

eLife · Dec 30, 2022Peer-reviewedNeuroscience