LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy
Susanne Nichterwitz, Jik Nijssen, Helena Storvall, Christoph Schweingruber, Laura Helen Comley, Ilary Allodi, Mirjam van der Lee, Qiaolin Deng, Rickard Sandberg, Eva Hedlund
This study uses LCM-seq to analyze transcriptional changes in SMA, identifying cell-type specific adaptations that explain resistance in ocular motor neurons.
Genome Research · Aug 20, 2020Peer-reviewedNeuroscience