Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
Diana Arseni, Takashi Nonaka, Max Henry Jacobsen, Alexey G. Murzin, Laura Cracco, Sew‐Yeu Peak‐Chew, Holly J. Garringer, Ito Kawakami, Hisaomi Suzuki, Misumoto Onaya, Yuko Saito, Shigeo Murayama, Changiz Geula, Rubén Vidal, Kathy L. Newell, , Benjamin Falcon
This study identifies heteromeric amyloid filaments composed of ANXA11 and TDP-43 in FTLD-TDP Type C using cryo-EM, revealing a new pathological mechanism.
Nature · Sep 11, 2024Peer-reviewedNeuroscience