Author
MRC Laboratory of Molecular BiologyORCID 0000-0001-7585-288XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Diana Arseni, Takashi Nonaka, Max Henry Jacobsen…·Benjamin Falcon
This study identifies heteromeric amyloid filaments composed of ANXA11 and TDP-43 in FTLD-TDP Type C using cryo-EM, revealing a new pathological mechanism.
Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu…·Sjors H. W. Scheres
This study identifies age-dependent formation of TMEM106B amyloid filaments in human brains using cryo-EM, showing they appear in older individuals but not younger ones.
Yang Yang, Diana Arseni, Wenjuan Zhang…·Michel Goedert
Cryo-EM shows brain-derived Aβ42 filaments adopt two related S-shaped protofilament folds: Type I dominates sporadic Alzheimer's, Type II familial Alzheimer's, other disorders and App^NL-F knock-in mice.