Electrophysiologically Targeted Biopsies Reveal the Transcriptional Landscape of Focal Epilepsy
Ashwin Viswanathan, Molly Murch, Abby L. Brand, Julia Lynn Furnari, Nathaniel W. Rolfe, Archana Yadav, Clara H. Stucke, Aayushi Mahajan, Juncheng Li, August D. Kahle, Misha Amini, Tristan T. Sands, Osama Al‐Dalahmah, Jeffrey N. Bruce, Brian J. A. Gill, , Catherine A. Schevon
This study uses electrophysiologically guided biopsies and single-nucleus RNA sequencing to identify transcriptional differences between seizure focus and ictal penumbra in focal epilepsy.
bioRxiv · Mar 10, 2026 · PreprintNeuroscience