Mammalian vesicular glutamate transporter VGLUT1 reduces synaptic vesicle superpool size and spontaneous release frequency.
Xiao Min Zhang, Urielle François, Kätlin Silm, María Florencia Angelo, Maria Busch, Mona Maged, Christelle Martin, Véronique Bernard, Fabrice P. Cordelières, Melissa Deshors, Stéphanie Pons, Uwe Maskos, Alexis‐Pierre Bemelmans, Sonja M. Wojcik, Salah El Mestikawy, , Étienne Herzog
The paper identifies a mechanism by which VGLUT1 increases synaptic vesicle clustering, reducing superpool size and spontaneous release frequency through interactions with endophilinA1 and intersectin1.
eLife · Oct 30, 2019Peer-reviewedNeuroscience