Molecular BiologyJournal of Biological ChemistryPeer-reviewed
A synthetic non-histone substrate provides insight into substrate targeting by the Gcn5 HAT and sirtuin HDACs
Anthony Rössl, Alix M. Denoncourt, Mong-Shang Lin, Michael Downey
The paper uses synthetic biology in yeast to show a shared sequence determines substrate selection for Gcn5 and sirtuins and identifies subunits of the Gcn5 complex that regulate non-histone acetylations.
10 citations