Alix M. Denoncourt

The paper identifies 7 novel polyP-binding proteins in E. coli linked to translation control and ribosome biogenesis, with specific roles for YihI and Rnr.

The paper investigates how Ddp1 and Ppx1 counter polyphosphate toxicity in yeast by analyzing stress responses and enzyme functions.

This study shows that internally produced polyP in human cells activates signaling pathways and alters gene and protein expression through ectopic expression of a bacterial polyP synthetase.

The paper identifies 8 new polyphosphorylated proteins in yeast, including vacuolar proteins, and suggests a feedback regulation model for polyP synthesis.

The paper uses synthetic biology in yeast to show a shared sequence determines substrate selection for Gcn5 and sirtuins and identifies subunits of the Gcn5 complex that regulate non-histone acetylations.