Sertraline enhances bacterial control by improving the pharmacodynamic -pharmacokinetic properties of frontline TB drugs
Kanika Bisht, Monica Yadav, Mahima Madan, Largee Biswas, Rajesh Pradhan, Rajeev Taliyan, Manjula Singh, Anita Kamra Verma, Vivek Rao
This study shows sertraline improves bacterial control in TB models by enhancing the pharmacodynamic-pharmacokinetic properties of TB drugs without altering their distribution or clearance.
bioRxiv · Jul 13, 2025 · PreprintMicrobiology