RNA Alternative Splicing and Polyadenylation and Regulation of the Glomerular Filtration Barrier
Monoj K Das, Amy Webb, Mahika Yarram, Christian Reilly, Lalith Punepalle Raveendrareddy, Claire Bryant, Rajgopal Govindarajan, Claire L. Moore, Shipra Agrawal
This study identifies altered alternative splicing and polyadenylation in glomerular genes during kidney disease models and demonstrates potential therapeutic modulation using antisense oligonucleotides.
Journal of the American Society of Nephrology · May 21, 2025Peer-reviewedMolecular Biology