Author

Mushaine Shih

University of Illinois Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:large language model· 1

Frequent Co-Authors

Chieh ChangiD· 2 shared Nobuko Suzuki· 2 shared Yan ZouiD· 2 shared Abdalla M. AbdrabouiD· 1 shared Alanur Tutar· 1 shared Aly Azeem KhaniD· 1 shared Amber C. LennoniD· 1 shared Andrew KangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Chieh ChangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AI-Guided CRISPR Screen Accelerates Discovery of New Drug Targets

Chenlin Zhao, Mushaine Shih, Sharif Ahmed, Steven Song, Amber C. Lennon, Julia M. Mayes, Mengqi Jonathan Fan, Pei-Ying Lo, Jason F. Perera, Alanur Tutar, Andrew Kang, Elizabeth Warren, Ryan A. McClure, Aly Azeem Khan, Shana O. Kelley, Abdalla M. Abdrabou

This study uses a CRISPR screen and AI to identify new drug targets for psoriasis, finding ALOX5 and OXTR as promising candidates with validated therapeutic effects.

bioRxiv · Feb 28, 2026 · PreprintGenomics

Two intrinsic timing mechanisms set start and end times for dendritic arborization of a nociceptive neuron

Nobuko Suzuki, Yan Zou, HaoSheng Sun, Kelsie Eichel, Meiyu Shao, Mushaine Shih, Kang Shen, Chieh Chang

The paper identifies two regulatory circuits that control the start and end times of dendritic arborization in nociceptive neurons through opposing regulation of the DMA-1 receptor.

Proceedings of the National Academy of Sciences · Nov 2, 2022Peer-reviewedNeuroscience

The kpc-1 3'UTR facilitates dendritic transport and translation of mRNAs for dendrite arborization of a mechanosensory neuron important for male courtship

Mushaine Shih, Yan Zou, Tarsis Ferreira, Nobuko Suzuki, Eunseo Kim, Chiou‐Fen Chuang, Chieh Chang

The paper shows that the kpc-1 3UTR is involved in dendrite arborization and self-avoidance in C. elegans mechanosensory neurons, promoting local protein synthesis and mRNA transport.

bioRxiv · Aug 3, 2021 · PreprintNeuroscience