Author
University of Massachusetts Chan Medical School
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Mihkel Ord, Natalia de Martin Garrido, Matthew J. Winters…·Norman E. Davey
The paper identifies a non-canonical helical binding motif in MAD1 that specifically interacts with Cyclin B1 to recruit CDK1 to the SAC, revealing a mechanism for B-type cyclin recognition.
Priyanka Madhu, Caroline Benz, Leandro Simonetti…·Ylva Ivarsson
The paper maps over 20,000 human protein-protein interactions mediated by short linear motifs using a peptide library screening approach.
Mihkel Örd, Matthew J. Winters, Mythili S. Subbanna…·Norman E. Davey
The paper identifies and characterizes cyclin-CDK docking motifs through high-throughput peptide binding assays and structural analysis, revealing a broader repertoire of motif types and binding mechanisms.
Mythili S. Subbanna, Matthew J. Winters, Mihkel Örd…·Peter M. Pryciak
The paper introduces SIMBA, a functional assay to quantify SLiM binding, showing in vivo binding strength correlates with in vitro affinity and revealing context-dependent recognition determinants.