Immunodominance is a poor predictor of vaccine-induced T follicular helper cell quality
Hyon‐Xhi Tan, MZM Zheng, Kathleen M. Wragg, Lydia Murdiyarso, Devaki Pilapitiya, A Kelly, Robyn Esterbauer, Christopher A. Gonelli, Adam K. Wheatley, Jennifer A. Juno
The paper investigates the relationship between CD4 T cell epitope immunodominance and vaccine-induced T follicular helper cell quality, finding that immunodominance is not predictive of helper quality.
bioRxiv · Jul 21, 2025 · PreprintImmunology