Robyn Esterbauer

Live attenuated YFV-17D vaccine induces robust B and T cell immunity in vaccine-draining lymph nodes

This study examines immune dynamics in lymph nodes after YFV-17D vaccination, identifying robust B and T cell responses and a conserved germinal center program across different vaccines.

Immunogen selection and prior immunity shape antibody breadth following immunisation with avian H5 hemagglutinin

This study shows that vaccine strain selection and prior immunity influence antibody breadth against avian H5 hemagglutinin in mice.

Novel monoclonal antibodies targeting distinct sites on placental binding P. falciparum antigen VAR2CSA synergistically enhance parasite phagocytosis

The paper identifies VAR2CSA-specific monoclonal antibodies that synergistically enhance phagocytosis of malaria-infected red blood cells when combined, but none inhibit CSA binding.

A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses

A chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and HKU-1 scaffold domains elicits potent neutralising antibodies and CD4 T cell help in mice and macaques.

Immunodominance is a poor predictor of vaccine-induced T follicular helper cell quality

The paper investigates the relationship between CD4 T cell epitope immunodominance and vaccine-induced T follicular helper cell quality, finding that immunodominance is not predictive of helper quality.

Memory T and B cells with recognition of avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines

The paper quantifies pre-existing human B cell responses to avian influenza H5 and H7 hemagglutinins and shows limited boosting by seasonal vaccines.