Single-cell Analysis of Attenuation-Driven Transcription Reveals New Principles of Bacterial Gene Regulation
Shafagh Moradian, N Ali, Rahul Jagadeesan, Volker Behrends, Andre Sanches Ribeiro, Christoph Engl
The paper shows that transcription attenuation modulates both burst size and frequency from a σ70 promoter, challenging previous views on frequency modulation and revealing cross-feeding as a strategy for controlling gene expression variation.
bioRxiv · Oct 6, 2025 · PreprintMicrobiology