Author

N. Al Rayyan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Whitt· 1 shared A. Zippelius· 1 shared B. Stamp· 1 shared C. Li· 1 shared H. Donninger· 1 shared J. A. Chesney· 1 shared J. Eaton· 1 shared K. Yaddanapudi· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Whitt

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Author profile →

1 paper

Recent·Most cited

Tumor-educated monocytes suppress T cells via adenosine and depletion of adenosine in the tumor microenvironment with adenosine deaminase enzyme promotes response to immunotherapy

O. S. Sarkar, H. Donninger, N. Al Rayyan, L. C. Chew, B. Stamp, X. Zhang, A. Whitt, C. Li, M. Hall, R. A. Mitchell, A. Zippelius, J. Eaton, J. A. Chesney, K. Yaddanapudi

This study shows that tumor-educated monocytes suppress T cells via adenosine and that depleting adenosine with PEG-ADA enhances immunotherapy response in preclinical models.

bioRxiv · Jun 22, 2022 · PreprintCell Biology