Author

N. Alachkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Pickard· 1 shared B. Calverley· 1 shared D. Norton· 1 shared J. Chang· 1 shared K. E. Kadler· 1 shared M. Muldoon· 1 shared P. Arvan· 1 shared P. Paszek· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Pickard

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2 papers

Recent·Most cited

Variability of the innate immune response is globally constrained by transcriptional bursting

N. Alachkar, D. Norton, Z. Wolkensdorfer, M. Muldoon, P. Paszek

The paper analyzes TLR-induced gene expression variability using single-cell data and stochastic models, showing that gene response heterogeneity is captured by mean-variance relationships.

bioRxiv · Feb 20, 2023Immunology

Preservation of circadian rhythms by the protein folding chaperone, BiP

A. Pickard, J. Chang, N. Alachkar, B. Calverley, R. Garva, P. Arvan, Q. J. Meng, K. E. Kadler

The paper shows that BiP and chemical chaperones strengthen circadian rhythms in fibroblasts under ER stress and prevent ER stress in tendon by regulating collagen synthesis.

bioRxiv · Oct 4, 2018Cell Biology