Author

N. Broguiere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 4 Approach:experimental assay· 3 Approach:deep learning· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. P. Lutolf· 3 shared D. Dutta· 2 shared F. Rivest· 2 shared G. Coukos· 2 shared K. Homicsko· 2 shared M. Lutolf· 2 shared N. Brandenberg· 2 shared S. Ragusa· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

M. P. Lutolf

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dissection and reconstruction of the colorectal cancer tumor microenvironment

N. Broguiere, L. F. Lorenzo-Martin, S. Ragusa, F. Rivest, N. Brandenberg, S. Hohnel, D. Dutta, M. Gueye, D. Alpern, B. Deplancke, L. Kandalaft, G. Coukos, K. Homicsko, M. P. Lutolf

This study reconstructs the colorectal cancer tumor microenvironment using patient-derived organoids and co-cultures, revealing how stromal cells influence cancer behavior and immune evasion.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Bioengineered human colon organoids with in vivo-like complexity and function

O. Mitrofanova, N. Broguiere, M. Nikolaev, M. P. Lutolf

This paper develops bioengineered human colon organoids that mimic in vivo complexity and function, enabling long-term study of gut physiology and disease.

bioRxiv · Oct 5, 2023 · PreprintBioengineering

3D confinement regulates stem cell fate

O. Y. Dudaryeva, A. Bucciarelli, G. Bovone, S. Jaydev, N. Broguiere, M. Al-Bayati, M. Lutolf, M. W. Tibbitt

This study shows that 3D geometric confinement influences human mesenchymal stem cell fate by modulating YAP localization and mechanotransduction pathways.

bioRxiv · May 2, 2021 · PreprintBioengineering

Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed autologous tumoroids

D. Dutta, F. Rivest, F. Lorenzo Martin, N. Broguiere, L. Tillard, S. Ragusa, N. Brandenberg, S. Hoehnel, D. Saugy, S. Rusakiewicz, K. Homicsko, G. Coukos, M. P. Lutolf

This paper develops a microarray-based assay to assess tumor-infiltrating lymphocyte (TIL) activity against autologous tumoroids, identifying responders to immunotherapy.

bioRxiv · Mar 30, 2021 · PreprintCancer Biology

Morphogenesis guided by 3D patterning of growth factors in biological matrices

N. Broguiere, I. Luechtefeld, L. Trachsel, D. Mazunin, J. Bode, M. Lutolf, M. Zenobi-Wong

The paper introduces a 2PP system for precise 3D patterning of growth factors in biological matrices, enabling axon guidance studies in brain-mimetic ECMs.

bioRxiv · Nov 7, 2019Bioengineering