Author

K. Homicsko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

G. Coukos· 3 shared D. Dutta· 2 shared D. Saugy· 2 shared F. Rivest· 2 shared M. P. Lutolf· 2 shared N. Brandenberg· 2 shared N. Broguiere· 2 shared S. Ragusa· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

G. Coukos

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3 papers

Recent·Most cited

Dissection and reconstruction of the colorectal cancer tumor microenvironment

N. Broguiere, L. F. Lorenzo-Martin, S. Ragusa, F. Rivest, N. Brandenberg, S. Hohnel, D. Dutta, M. Gueye, D. Alpern, B. Deplancke, L. Kandalaft, G. Coukos, K. Homicsko, M. P. Lutolf

This study reconstructs the colorectal cancer tumor microenvironment using patient-derived organoids and co-cultures, revealing how stromal cells influence cancer behavior and immune evasion.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma

J. Chiffelle, D. Barras, R. Petremand, A. Orcurto, S. Bobisse, M. Arnaud, A. Auger, B. Navarro Rodrigo, E. Ghisoni, C. Sauvage, D. Saugy, A. Michel, B. Murgues, N. Fahr, M. Imbimbo, , G. Coukos

This study tracks tumor-reactive TIL clonotypes in melanoma patients before and after TIL-ACT to identify factors associated with clinical response.

bioRxiv · Jul 21, 2023 · PreprintCancer Biology

Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed autologous tumoroids

D. Dutta, F. Rivest, F. Lorenzo Martin, N. Broguiere, L. Tillard, S. Ragusa, N. Brandenberg, S. Hoehnel, D. Saugy, S. Rusakiewicz, K. Homicsko, G. Coukos, M. P. Lutolf

This paper develops a microarray-based assay to assess tumor-infiltrating lymphocyte (TIL) activity against autologous tumoroids, identifying responders to immunotherapy.

bioRxiv · Mar 30, 2021 · PreprintCancer Biology