Author

D. Alpern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

B. Deplancke· 5 shared J. Russeil· 3 shared V. Gardeux· 3 shared J. Pezoldt· 2 shared M. Zachara· 2 shared R. Ferrero· 2 shared A. Kratzel· 1 shared A. Meireles-Filho· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersCell Biology

B. Deplancke

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Author profile →

5 papers

Recent·Most cited

Dissection and reconstruction of the colorectal cancer tumor microenvironment

N. Broguiere, L. F. Lorenzo-Martin, S. Ragusa, F. Rivest, N. Brandenberg, S. Hohnel, D. Dutta, M. Gueye, D. Alpern, B. Deplancke, L. Kandalaft, G. Coukos, K. Homicsko, M. P. Lutolf

This study reconstructs the colorectal cancer tumor microenvironment using patient-derived organoids and co-cultures, revealing how stromal cells influence cancer behavior and immune evasion.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion

R. Ferrero, P. Rainer, J. Russeil, M. Zachara, J. Pezoldt, G. van Mierlo, V. Gardeux, W. Saelens, D. Alpern, L. Favre, S. Mantziari, T. Zingg, N. Pitteloud, M. Suter, M. Matter, , B. Deplancke

The paper identifies an omental-specific stromal population that inhibits adipogenesis via IGFBP2 secretion in human adipose tissue.

bioRxiv · May 1, 2023Cell Biology

Mammalian adipogenesis regulators (Aregs) exhibit robust non- and anti-adipogenic properties that arise with age and involve retinoic acid signalling

M. Zachara, P. Y. Rainer, J. Russeil, H. Hashimi, D. Alpern, R. Ferrero, M. Litovchenko, B. Deplancke

The paper characterizes CD142+ adipose stem and precursor cells (ASPCs) and shows their non- and anti-adipogenic properties emerge with age via retinoic acid signaling.

bioRxiv · Feb 24, 2021 · PreprintCell Biology

Disparate temperature-dependent virus - host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

P. V'kovski, M. Gultom, J. N. Kelly, S. Steiner, J. Russeil, B. Mangeat, E. Cora, J. Pezoldt, M. Holwerda, A. Kratzel, L. Laloli, M. Wider, J. Portmann, T. T. N. Thao, N. Ebert, , R. Dijkman

This study compares temperature-dependent replication and immune response dynamics of SARS-CoV-2 and SARS-CoV in human airway epithelial cells, highlighting differences in their antiviral responses and transmission efficiency.

bioRxiv · Apr 27, 2020Microbiology

A highly parallel, automated platform enabling individual or sequential ChIP of histone marks and transcription factors

R. Dainese, V. Gardeux, G. Llimos, D. Alpern, J. Y. Jiang, A. Meireles-Filho, B. Deplancke

This paper introduces FloChIP, a microfluidic platform for automated ChIP-seq that improves speed, throughput, and sensitivity compared to traditional methods.

bioRxiv · Aug 7, 2019Bioengineering