Regulation of NRF2 by Phosphoinositides and Small Heat Shock Proteins
C. Chen, M. Chen, T. Wen, P. Awasthi, N. D. Carrillo, R. A. Anderson, V. L. Cryns
This study shows that PIPKIγ and HSP27 regulate NRF2 stability and function, promoting stress resistance and suggesting them as potential drug targets in cancer.
bioRxiv · Oct 26, 2023 · PreprintCancer Biology