Author

N. Descostes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

D. Reinberg· 3 shared A. Leibholz· 1 shared B. Sieriebriennikov· 1 shared C. Desplan· 1 shared C. Opachaloemphan· 1 shared D. Bready· 1 shared D. G. Placantonakis· 1 shared F. Carmona-Aldana· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersPhysiology

D. Reinberg

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Insulin signaling and extended longevity in ants

H. Yan, C. Opachaloemphan, F. Carmona-Aldana, G. Mancini, J. Mlejnek, N. Descostes, B. Sieriebriennikov, A. Leibholz, X. Zhou, L. Ding, M. Traficante, C. Desplan, D. Reinberg

The paper investigates how insulin signaling and anti-insulin mechanisms in ants link reproduction to extended longevity through gene expression analysis in different castes.

bioRxiv · Jun 25, 2022 · PreprintPhysiology

The H3K36me2 writer-reader dependency in H3K27M-DIPG

J.-R. Yu, G. LeRoy, D. Bready, J. D. Frenster, R. Saldana-Meyer, Y. Jin, N. Descostes, J. M. Stafford, D. G. Placantonakis, D. Reinberg

This study identifies NSD1/2 as key writers and LEDGF/HDGF2 as readers of H3K36me2 in H3K27M-DIPG, showing their role in tumor proliferation and suggesting therapeutic targeting.

bioRxiv · Jan 6, 2021Cancer Biology

Active and repressed chromatin domains exhibit distinct nucleosome segregation during DNA replication

T. Escobar, O. Oksuz, N. Descostes, R. Bonasio, D. Reinberg

The paper investigates nucleosome inheritance during DNA replication in mouse embryonic stem cells, finding that repressed chromatin domains retain parental nucleosomes while active domains do not.

bioRxiv · Jan 17, 2019Biochemistry