Author

R. Saldana-Meyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. Reinberg· 2 shared C.-H. Lee· 1 shared D. Bready· 1 shared D. G. Placantonakis· 1 shared D. Grau· 1 shared G. LeRoy· 1 shared J. D. Frenster· 1 shared J. M. Stafford· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

D. Reinberg

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2 papers

Recent·Most cited

The H3K36me2 writer-reader dependency in H3K27M-DIPG

J.-R. Yu, G. LeRoy, D. Bready, J. D. Frenster, R. Saldana-Meyer, Y. Jin, N. Descostes, J. M. Stafford, D. G. Placantonakis, D. Reinberg

This study identifies NSD1/2 as key writers and LEDGF/HDGF2 as readers of H3K36me2 in H3K27M-DIPG, showing their role in tumor proliferation and suggesting therapeutic targeting.

bioRxiv · Jan 6, 2021Cancer Biology

Distinct stimulatory mechanisms regulate the catalytic activity of Polycomb Repressive Complex 2 (PRC2)

C.-H. Lee, M. Holder, D. Grau, R. Saldana-Meyer, R. A. Ganai, J. Zhang, M. Wang, M.-W. Dobenecker, D. Reinberg, K.-J. Armache

The paper shows that EZH1 and EZH2, two catalytic subunits of PRC2, are differentially activated to regulate H3K27 methylation, with AEBP2 adding additional stimulation.

bioRxiv · Nov 3, 2017Biochemistry