Author

G. LeRoy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

D. Reinberg· 2 shared A. Tsirigos· 1 shared D. Bready· 1 shared D. G. Placantonakis· 1 shared E. O. Mazzoni· 1 shared H. Cho· 1 shared H. Ortabozkoyun Kara· 1 shared J. A. Skok· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

D. Reinberg

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2 papers

Recent·Most cited

The H3K36me2 writer-reader dependency in H3K27M-DIPG

J.-R. Yu, G. LeRoy, D. Bready, J. D. Frenster, R. Saldana-Meyer, Y. Jin, N. Descostes, J. M. Stafford, D. G. Placantonakis, D. Reinberg

This study identifies NSD1/2 as key writers and LEDGF/HDGF2 as readers of H3K36me2 in H3K27M-DIPG, showing their role in tumor proliferation and suggesting therapeutic targeting.

bioRxiv · Jan 6, 2021Cancer Biology

A CRISPR Screen Identifies Myc-associated Zinc Finger Protein (MAZ) as an Insulator Functioning at CTCF boundaries in Hox Clusters

H. Ortabozkoyun Kara, P.-Y. Huang, H. Cho, V. Narendra, G. LeRoy, J. A. Skok, A. Tsirigos, E. O. Mazzoni, D. Reinberg

The paper identifies MAZ as an insulator functioning at CTCF boundaries in Hox clusters, contributing to genomic architecture during differentiation.

bioRxiv · Aug 25, 2020Biochemistry