Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression
D. J. Beech, V. Caolo, M. Debant, N. Endesh, S. Futers, L. Lichtenstein, G. Parsonage, E. A. V. Jones
The paper shows that Piezo1 channels activate ADAM10 to regulate Notch1 cleavage and gene expression in response to mechanical force.
bioRxiv · Aug 12, 2019 · PreprintCell Biology