Author

N. Fuggetta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

G. Drin· 3 shared M. Magdeleine· 2 shared A. A. Bello· 1 shared A. Copic· 1 shared A. MARTINET· 1 shared A. R. D. Araujo· 1 shared A. R. THIAM· 1 shared A. Seminara· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiochemistry

G. Drin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Surface tension-driven sorting of human perilipins on lipid droplets

A. R. D. Araujo, A. A. Bello, J. Bigay, C. Franckhauser, R. Gautier, J. Cazareth, D. Kovacs, F. Brau, N. Fuggetta, A. Copic, B. Antonny

The paper investigates how different human perilipins bind to lipid droplets by showing their varying affinities based on surface tension and lipid composition.

bioRxiv · Feb 12, 2024Biochemistry

Reconstitution of ORP-mediated lipid exchange process coupled to PI(4)P metabolism

N. Fuggetta, N. Rigolli, M. Magdeleine, A. Seminara, G. Drin

This study investigates how ORP-mediated lipid exchange and PI(4)P metabolism create sterol gradients between ER and Golgi membranes in vitro and estimate their cellular impact.

bioRxiv · Aug 4, 2023 · PreprintBiochemistry

MOSPD2 a new endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis

M. ZOUIOUICH, T. DI MATTIA, A. MARTINET, J. EICHLER, C. WENDLING, N. TOMISHIGE, E. GRANDGIRARD, N. FUGGETTA, C. RAMAIN, G. MIZZON, C. Dumesnil, M. CARPENTIER, B. REINA-SAN-MARTIN, C. MATHELIN, Y. Schwab, , F. ALPY

This study identifies MOSPD2 as an ER-lipid droplet tether that regulates LD homeostasis through its CRAL-TRIO domain.

bioRxiv · Feb 11, 2022Cell Biology

Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts set unanticipated rules on lipid transfer

S. Ikhlef, N.-F. Lipp, V. Delfosse, N. Fuggetta, W. Bourguet, M. Magdeleine, G. Drin

This study investigates how lipid transfer proteins exchange phosphatidylserine and phosphatidylinositol 4-phosphate, revealing that their transfer speed inversely depends on ligand affinity and that they cannot use PI(4,5)P2 for exchange.

bioRxiv · Jul 16, 2021Biochemistry