Author

N. Gassler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Bauer· 2 shared A. Henke· 1 shared A. Press· 1 shared A. Stallmach· 1 shared B. Löffler· 1 shared C. Ehrhardt· 1 shared C. Häring· 1 shared D. Haziri· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

M. Bauer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selective uptake into inflamed human intestinal tissue and immune cell targeting by wormlike polymer micelles

E. Gardey, F. H. Sobotta, D. Haziri, P. C. Grunert, M. T. Kuchenbrod, F. V. Gruschwitz, S. Hoeppener, M. Schumann, N. Gassler, A. Stallmach, J. C. Brendel

This study shows that wormlike polymer micelles selectively enter inflamed human intestinal tissue and target immune cells, offering potential for IBD treatment.

bioRxiv · Jan 26, 2021Physiology

RIPK3 promoter hypermethylation in hepatocytes protects from bile acid induced inflammation and necroptosis

J. Hoff, L. Xiong, T. Kammann, S. Neugebauer, J. M. Micheel, M. Ghait, S. D. Deshmukh, A. Press, M. Bauer, N. Gassler

The paper shows that RIPK3 promoter hypermethylation in hepatocytes reduces RIPK3 expression, protecting against bile acid-induced inflammation and necroptosis, but RIPK3 induction may signal danger in cholestatic liver diseases.

bioRxiv · Jan 15, 2021 · PreprintBiochemistry

Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and correlation to tissue damage

S. Deinhardt-Emmer, D. Wittschieber, J. Sanft, S. Kleemann, S. Elschner, K. F. Haupt, V. Vau, C. Häring, J. Rödel, A. Henke, C. Ehrhardt, M. Bauer, M. Philipp, N. Gassler, S. Nietzsche, , G. Mall

The paper maps SARS-CoV-2 RNA distribution in 11 deceased COVID-19 patients and correlates it with tissue damage and systemic inflammation.

bioRxiv · Jul 1, 2020Immunology