Author

S. Deinhardt-Emmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Hornung· 3 shared A. Henke· 2 shared B. Löffler· 2 shared C. Ehrhardt· 2 shared C. Häring· 2 shared S. Nietzsche· 2 shared A. Piekielko-Witkowska· 1 shared A. S. Mosig· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

F. Hornung

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 and its ORF3a, E and M viroporins activate inflammasome in human macrophages and induce of IL-1α in pulmonary epithelial and endothelial cells

M. Abrozek-Latecka, P. Kozlowski, G. Hoser, M. Bandyszewska, K. Hanusek, D. Nowis, J. Golab, M. Grzanka, A. Piekielko-Witkowska, L. Schulz, F. Hornung, S. Deinhardt-Emmer, E. Kozlowska, T. Skirecki

This study shows SARS-CoV-2 viroporins ORF3a, E, and M activate inflammasomes in macrophages and induce IL-1α release in pulmonary epithelial and endothelial cells, contributing to immunothrombosis in COVID-19.

bioRxiv · Nov 13, 2023 · PreprintImmunology

Nanoscopy on the Chea(i)p

B. Diederich, O. I. Helle, P. Then, P. Carravilla, K. O. Schink, F. Hornung, S. Deinhardt-Emmer, C. Eggeling, B. S. Ahluwalia, R. Heintzmann

This paper presents a low-cost, 3D-printed super-resolution microscope using a cellphone for imaging and processing, achieving 100nm resolution and enabling live imaging of SARS-CoV-2 viroids.

bioRxiv · Sep 4, 2020 · PreprintMicrobiology

SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction

S. Deinhardt-Emmer, S. Böttcher, C. Häring, L. Giebeler, A. Henke, R. Zell, F. Hornung, C. Brandt, M. Marquet, A. S. Mosig, M. W. Pletz, M. Schacke, J. Roedel, R. Heller, S. Nietzsche, , C. Ehrhardt

This study shows SARS-CoV-2 infects alveolar epithelial cells, causing inflammation and barrier dysfunction, while endothelial cells are damaged through cytokine release from infected epithelial cells.

bioRxiv · Aug 31, 2020Microbiology

Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and correlation to tissue damage

S. Deinhardt-Emmer, D. Wittschieber, J. Sanft, S. Kleemann, S. Elschner, K. F. Haupt, V. Vau, C. Häring, J. Rödel, A. Henke, C. Ehrhardt, M. Bauer, M. Philipp, N. Gassler, S. Nietzsche, , G. Mall

The paper maps SARS-CoV-2 RNA distribution in 11 deceased COVID-19 patients and correlates it with tissue damage and systemic inflammation.

bioRxiv · Jul 1, 2020Immunology