Author

N. Gour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. M. Yong· 2 shared J. Feng· 2 shared R. Yee· 2 shared S. Lajoie· 2 shared W. Shi· 2 shared Y. Yuan· 2 shared Y. Zhang· 2 shared A. L. Scott· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

H. M. Yong

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Air pollution drives macrophage senescence through a phagolysosome-15-lipoxygenase pathway

S. A. Thomas, H. M. Yong, A. M. Rule, N. Gour, S. Lajoie

This study shows urban particulate matter induces macrophage senescence through a phagolysosome-15-lipoxygenase pathway, independent of inflammasome or scavenger receptor pathways.

ImmunoHorizons · Apr 16, 2024Peer-reviewedImmunology

Primary lung fibroblasts respond to IL-33, IL-13, and IL-17A by secreting factors that activate macrophages

J. Venezia, N. Gour, J. Loube, W. Mitzner, A. L. Scott

This study shows that lung fibroblasts exposed to IL-33, IL-13, and IL-17A secrete factors that activate macrophages, highlighting their role in lung remodeling and emphysema progression.

bioRxiv · Feb 28, 2023 · PreprintImmunology

Epigenetic regulation of epithelial dectin-1 through an IL-33-STAT3 axis in allergic disease

H. M. Yong, N. Gour, D. Sharma, S. M. Khalil, A. P. Lane, S. Lajoie

This study identifies an IL-33-STAT3 axis that epigenetically represses dectin-1 in epithelial cells, contributing to allergic disease.

bioRxiv · Nov 1, 2020Immunology

Ranking of Major Classes of Antibiotics for Activity against Stationary Phase Pseudomonas aeruginosa and Identification of Clinafloxacin + Cefuroxime + Gentamicin Drug Combination that Eradicates Persistent P. aeruginosa Infection in a Murine Cystic Fibrosis Model

Y. Yuan, R. Yee, N. Gour, X. Dong, J. Feng, W. Shi, Y. Zhang

bioRxiv · Jun 30, 2019 · PreprintMicrobiology

A Drug Combination Approach Targeting Both Growing Bacteria and Dormant Persisters Eradicate Persistent Staphylococcus aureus Biofilm Infection

R. Yee, Y. Yuan, A. Tarff, C. Brayton, N. Gour, J. Feng, W. Shi, Y. Zhang

This study demonstrates that combining antibiotics targeting both growing bacteria and persisters eradicates S. aureus biofilm infections more effectively than current treatments.

bioRxiv · Jun 28, 2019 · PreprintMicrobiology