DISRUPTOR: Computational identification of oncogenic mutants disrupting protein interactions
V. Kugler, A. Lieb, N. Guerin, B. R. Donald, E. Stefan, T. Kaserer
DISRUPTOR identifies oncogenic mutations disrupting protein interactions using an Osprey-based protocol, validated on clinically relevant mutations and confirmed experimentally.
bioRxiv · Nov 2, 2022 · PreprintCancer Biology