Author

N. I. Clarke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:electronic health records· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. J. Royle· 5 shared G. Larocque· 3 shared P. J. La-Borde· 2 shared B. J. Wilson· 1 shared C. Kuey· 1 shared D. J. Moore· 1 shared L. A. Wood· 1 shared N. J. Carter· 1 shared

Activity by Year

2016-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersCell Biology

S. J. Royle

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Author profile →

5 papers

Recent·Most cited

Intracellular nanovesicles mediate integrin trafficking during cell migration

G. Larocque, P. J. La-Borde, B. J. Wilson, N. I. Clarke, D. J. Moore, P. T. Caswell, S. J. Royle

This study identifies intracellular nanovesicles (INVs) as mediators of integrin trafficking during cell migration, showing that TPD52-like proteins regulate this process and affect cell migration and invasion.

bioRxiv · Aug 19, 2020Cell Biology

Tumor Protein D54 defines a new class of intracellular transport vesicle

G. Larocque, P. J. La-Borde, N. I. Clarke, N. J. Carter, S. J. Royle

The paper identifies TPD54 as defining a new class of intracellular transport vesicles called INVs, which have specific cargo, R-SNAREs, and Rab GTPases.

bioRxiv · Aug 12, 2019Cell Biology

Unintended inhibition of protein function using GFP nanobodies in human cells

C. Kuey, G. Larocque, N. I. Clarke, S. J. Royle

The paper demonstrates that GFP nanobodies can inhibit protein function in human cells, limiting their use for knocksideways experiments.

bioRxiv · May 30, 2019Cell Biology

FerriTag: A Genetically-Encoded Inducible Tag for Correlative Light-Electron Microscopy

N. I. Clarke, S. J. Royle

This paper introduces FerriTag, a genetically-encoded inducible tag for correlative light-electron microscopy, demonstrating its utility in labeling and visualizing proteins at nanoscale resolution.

bioRxiv · Dec 18, 2016Cell Biology

Hot-wiring clathrin-mediated endocytosis in human cells

L. A. Wood, N. I. Clarke, S. Sarkar, S. J. Royle

This paper introduces a method to induce clathrin-mediated endocytosis on demand in human cells and uses it to study interactions between clathrin and the β2 subunit of the AP2 complex.

bioRxiv · Jul 4, 2016Cell Biology