Author

P. T. Caswell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Akhil Shp· 1 shared A. Forrester· 1 shared A. Pinet· 1 shared B. J. Wilson· 1 shared B. Lombard· 1 shared B. Wilson· 1 shared C. A. Valades-Cruz· 1 shared C. Flett· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Akhil Shp

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3 papers

Recent·Most cited

Growth factor-induced desialylation for the fast control of endocytosis

E. MacDonald, A. Forrester, C. A. Valades-Cruz, T. D. Madsen, J. Hetmanski, E. Dransart, Y. Ng, R. Godbole, A. Akhil Shp, L. Leconte, V. Chambon, D. Ghosh, A. Pinet, D. D. Bhatia, B. Lombard, , L. Johannes

The paper shows that growth factors induce rapid desialylation of cell surface glycoproteins, enabling reversible changes in glycan structure and function through galectin-mediated endocytosis.

Nature Cell Biology · Feb 21, 2025Peer-reviewedCell Biology

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

B. Wilson, J. Gemperle, C. Lawless, C. Flett, M. Hartshorn, E. Hinde, T. Harrison, M. Chastney, S. Taylor, J. Allen, P. T. Caswell

The paper uses proximity labeling to identify protein complexes associated with Rab4, Rab11a, and Rab25 in cancer cells, revealing their roles in endocytic recycling and cell migration.

bioRxiv · May 12, 2022Cell Biology

Intracellular nanovesicles mediate integrin trafficking during cell migration

G. Larocque, P. J. La-Borde, B. J. Wilson, N. I. Clarke, D. J. Moore, P. T. Caswell, S. J. Royle

This study identifies intracellular nanovesicles (INVs) as mediators of integrin trafficking during cell migration, showing that TPD52-like proteins regulate this process and affect cell migration and invasion.

bioRxiv · Aug 19, 2020Cell Biology