Detection of Viral RNA Fragments in Human iPSC-Cardiomyocytes following Treatment with Extracellular Vesicles from SARS-CoV-2 Coding-Sequence-Overexpressing Lung Epithelial Cells
Y. Kwon, S. B. Nukala, S. Srivastava, H. Miyamoto, N. I. Ismail, J. Rehman, S.-B. Ong, W. H. Lee, S.-G. Ong
This study shows that SARS-CoV-2 RNA can enter cardiomyocytes via extracellular vesicles from infected lung cells, leading to inflammation-related gene upregulation.
bioRxiv · May 14, 2020Cell Biology