Author

N. J. Brideau

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Zhang· 1 shared D. Lyumkis· 1 shared P. D. Hsu· 1 shared P. Lotfy· 1 shared P. R. Griffin· 1 shared S. J. Novick· 1 shared S. Konermann· 1 shared T. Strutzenberg· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

C. Zhang

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1 paper

Recent·Most cited

Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d

C. Zhang, S. Konermann, N. J. Brideau, P. Lotfy, S. J. Novick, T. Strutzenberg, P. R. Griffin, P. D. Hsu, D. Lyumkis

The paper determines the structural basis of CRISPR-Cas13d's RNA-guided ribonuclease activity through cryo-EM and biochemical analysis, revealing its molecular architecture and activation mechanisms.

bioRxiv · May 4, 2018Biochemistry