Author

T. Strutzenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:structural biology· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

D. Lyumkis· 2 shared A. Biswas· 1 shared A. Haldane· 1 shared C. Zhang· 1 shared D. Passos· 1 shared I. Choudhuri· 1 shared M. Li· 1 shared N. Deng· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

D. Lyumkis

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2 papers

Recent·Most cited

Mechanisms of HIV-1 Integrase Resistance to Dolutegravir and Potent Inhibition of Drug Resistant Variants

M. Li, D. Passos, Z. Shan, S. J. Smith, Q. Sun, A. Biswas, I. Choudhuri, T. Strutzenberg, A. Haldane, N. Deng, Z. Li, X.-Z. Zhao, T. R. Burke, R. M. Levy, S. H. Hughes, , D. Lyumkis

The paper investigates mechanisms of HIV-1 integrase resistance to Dolutegravir and shows that 4d is more effective against resistant variants.

bioRxiv · Dec 4, 2022Biophysics

Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d

C. Zhang, S. Konermann, N. J. Brideau, P. Lotfy, S. J. Novick, T. Strutzenberg, P. R. Griffin, P. D. Hsu, D. Lyumkis

The paper determines the structural basis of CRISPR-Cas13d's RNA-guided ribonuclease activity through cryo-EM and biochemical analysis, revealing its molecular architecture and activation mechanisms.

bioRxiv · May 4, 2018Biochemistry