Author

N. Jillette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

A. W. Cheng· 5 shared J. J. Zhu· 3 shared C. C. Lau· 1 shared M. Du· 1 shared X.-N. Li· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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5 shared papersBioengineering

A. W. Cheng

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Targeted directional kilobase sequence insertion by combining prime editing with recombinases or integrases

N. Jillette, J. J. Zhu, A. W. Cheng

This paper introduces PRIMAS, a method combining prime editing with recombinases/integrases to insert kilobase sequences directionally into genomes.

bioRxiv · May 25, 2022 · PreprintBioengineering

Local recruitment of DNA repair proteins enhances CRISPR-ssODN-HDR editing

N. Jillette, J. J. Zhu, A. W. Cheng

This study enhances CRISPR-ssODN-HDR editing by recruiting DNA repair proteins to Cas9 cut sites using two strategies, increasing precise edits.

bioRxiv · Apr 13, 2022 · PreprintBioengineering

C11orf95-RELA Reprograms 3D Epigenome in Supratentorial Ependymoma

J. J. Zhu, N. Jillette, X.-N. Li, A. W. Cheng, C. C. Lau

This study investigates how the C11orf95-RELA fusion protein reprograms the 3D epigenome in supratentorial ependymoma, revealing its role in chromatin state modulation and transcriptional reprogramming.

bioRxiv · Jun 4, 2020Cancer Biology

Split Selectable Markers

N. Jillette, M. Du, A. W. Cheng

This paper introduces split selectable markers to enable selection of multiple unlinked transgenes in lentiviral transgenesis and CRISPR/Cas biallelic knock-ins.

bioRxiv · Jan 23, 2019Bioengineering

CRISPR Artificial Splicing Factors

N. Jillette, A. W. Cheng

This paper engineers CRISPR Artificial Splicing Factors (CASFx) to control alternative splicing through differential positioning and inducible systems.

bioRxiv · Sep 30, 2018Bioengineering