Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer
K. E. Blise, S. Sivagnanam, C. B. Betts, K. Betre, N. Kirchberger, B. Tate, E. E. Furth, A. Dias Costa, J. A. Nowak, B. M. Wolpin, R. H. Vonderheide, J. Goecks, L. M. Coussens, K. Byrne
This study uses machine learning to analyze spatial proteomic data from pancreatic cancer patients, linking T cell function and localization to neoadjuvant CD40 therapy and clinical outcomes.
bioRxiv · Oct 20, 2023Cancer Biology