Author

E. E. Furth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:clustering· 1

Frequent Co-Authors

J. Llewellyn· 2 shared R. G. Wells· 2 shared A. Dhand· 1 shared A. Dias Costa· 1 shared A. E. Loneker· 1 shared A. K. Rustgi· 1 shared A. Naji· 1 shared A. R. Hall· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

J. Llewellyn

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer

K. E. Blise, S. Sivagnanam, C. B. Betts, K. Betre, N. Kirchberger, B. Tate, E. E. Furth, A. Dias Costa, J. A. Nowak, B. M. Wolpin, R. H. Vonderheide, J. Goecks, L. M. Coussens, K. Byrne

This study uses machine learning to analyze spatial proteomic data from pancreatic cancer patients, linking T cell function and localization to neoadjuvant CD40 therapy and clinical outcomes.

bioRxiv · Oct 20, 2023Cancer Biology

Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts

K. Weinfurtner, D. Tischfield, G. McClung, J. Crainic, J. Gordan, J. Jiao, E. E. Furth, W. Li, E. Tuzneen Supan, G. J. Nadolski, S. J. Hunt, D. E. Kaplan, T. P. Gade

This study shows that human GM-CSF and IL-3 expression in humanized mice increases immune cell infiltration in HCC tumors, improving the model's resemblance to human disease.

bioRxiv · Oct 5, 2023Cancer Biology

Injury and a program of fetal wound healing in the fetal and neonatal extrahepatic bile duct

I. E. M. de Jong, M. L. Hunt, D. Chen, Y. Du, J. Llewellyn, K. Gupta, D. A. Erxleben, F. Rivas, A. R. Hall, E. E. Furth, A. Naji, C. Liu, A. Dhand, J. A. Burdick, M. G. Davey, , R. G. Wells

This study investigates the fetal response to injury in extrahepatic bile ducts (EHBDs) and identifies a fetal wound healing program characterized by high molecular weight HA, which may lead to obstruction in biliary atresia.

bioRxiv · Dec 15, 2022 · PreprintPhysiology

Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment

N. Li, Q. Zhu, Y. Tian, K. J. Ahn, X. Wang, Z. Cramer, I. W. Folkert, P. Yu, J. Jou, S. Adams-Tzivelekidis, P. Sehgal, N. N. Mahmoud, C. B. Aarons, R. E. Roses, A. Thomas-Tikhonenko, , C. J. Lengner

This study maps and models human colorectal carcinoma interactions with the tumor microenvironment using single-cell transcriptomics and tumoroid cultures, showing how tumoroids suppress inflammation and reprogram macrophages.

bioRxiv · Sep 13, 2022Cancer Biology

Glisson's capsule structure and function is altered in cirrhotic patients irrespective of etiology

J. Llewellyn, C. Fede, A. E. Loneker, C. S. Friday, M. W. Hast, N. D. Theise, E. E. Furth, M. Guido, C. Stecco, R. G. Wells

This study examines changes in Glisson's capsule in liver disease, finding increased thickness and cellularity in cirrhosis regardless of cause, altered matrix composition, and reduced mechanical stiffness.

bioRxiv · Aug 28, 2022 · PreprintPhysiology