Author

N. M. Chasen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Assay:metagenomics· 1

Frequent Co-Authors

R. D. Etheridge· 2 shared A. J. Stasic· 1 shared B. Asady· 1 shared C. B. Di Capua· 1 shared C. L. de Graffenried· 1 shared E. J. Dykes· 1 shared E. Tevere· 1 shared I. Y. Kuo· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

R. D. Etheridge

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4 papers

Recent·Most cited

TcHRG plays a central role in orchestrating heme uptake in Trypanosoma cruzi epimastigotes

E. Tevere, C. B. Di Capua, N. M. Chasen, R. D. Etheridge, J. A. Cricco

This study identifies TcHRG as a key regulator of heme uptake in T. cruzi epimastigotes, showing it mediates heme acquisition from both hemoglobin and hemin sources.

bioRxiv · Apr 5, 2023 · PreprintBiochemistry

Endocytosis in Trypanosoma cruzi Depends on Proper Recruitment and Regulation of Functionally Redundant Myosin Motors

N. M. Chasen, M. G. Etheridge, P. C. Campbell, C. L. de Graffenried, K. Bimpeh, K. M. Hines, R. D. Etheridge

This study identifies MyoF and MyoC as functionally redundant myosin motors essential for endocytosis in T. cruzi, with MyAP playing dual roles in myosin targeting and regulation.

bioRxiv · Nov 17, 2022 · PreprintMicrobiology

Calcium signaling through a Transient Receptor Channel is important for Toxoplasma gondii growth

K. M. Marquez-Nogueras, N. M. Chasen, M. A. Hortua Triana, I. Y. Kuo, S. N. J. Moreno

This study identifies TgTRPPL-2 as a Ca2+ channel in Toxoplasma gondii essential for growth and signaling, with pharmacological inhibitors showing efficacy against the parasite.

bioRxiv · Oct 9, 2020Microbiology

The Toxoplasma Vacuolar H+-ATPase regulates intracellular pH, and impacts the maturation of essential secretory proteins

A. J. Stasic, N. M. Chasen, E. J. Dykes, S. A. Vella, B. Asady, V. J. Starai, S. Moreno

This study identifies a dual role for the Toxoplasma V-H+-ATPase in protecting against ionic stress and facilitating the maturation of secretory proteins in endosomal-like compartments.

bioRxiv · Jan 9, 2019Microbiology