Author

I. Y. Kuo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. M. Marquez-Nogueras· 3 shared Q. Cao· 2 shared R. M. Knutila· 2 shared A. B. Chapman· 1 shared A. V. Zima· 1 shared B. Elliott· 1 shared D. Y. Barefield· 1 shared E. Bovo· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersPhysiology

K. M. Marquez-Nogueras

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension

B. Elliott, K. M. Marquez-Nogueraz, P. Thuo, E. DiNello, R. M. Knutila, G. E. Fritzmann, M. Willis, A. B. Chapman, Q. Cao, D. Y. Barefield, I. Y. Kuo

This study shows that cardiac polycystin-2 is involved in natriuretic peptide production, and its absence leads to hypertension in ADPKD mice.

bioRxiv · Jan 2, 2024Physiology

Utilization of the genetically encoded calcium indicator Salsa6F in cardiac applications

K. M. Marquez-Nogueras, E. Bovo, Q. Cao, A. V. Zima, I. Y. Kuo

The paper evaluates the use of the genetically encoded calcium indicator Salsa6F in cardiac applications, comparing it to Fluo-4AM and demonstrating its utility in measuring calcium transients in cardiomyocytes and heart preparations.

bioRxiv · Nov 22, 2023Physiology

TRiPPing the sensors: The osmosensing pathway of Polycystin 2

K. M. Marquez-Nogueras, R. M. Knutila, V. Vuchkovska, I. Y. Kuo

This study identifies osmolarity as a physiological activator of ER-localized PC2 and shows that MAP4-dependent microtubule stabilization is required for PC2's role in osmosensing and urine concentration.

bioRxiv · May 9, 2023 · PreprintPhysiology

Calcium signaling through a Transient Receptor Channel is important for Toxoplasma gondii growth

K. M. Marquez-Nogueras, N. M. Chasen, M. A. Hortua Triana, I. Y. Kuo, S. N. J. Moreno

This study identifies TgTRPPL-2 as a Ca2+ channel in Toxoplasma gondii essential for growth and signaling, with pharmacological inhibitors showing efficacy against the parasite.

bioRxiv · Oct 9, 2020Microbiology