H. Dai

Genomic insights into photosymbiotic evolution in Tridacna squamosa

This study presents the first complete genome of Tridacna squamosa and integrates multi-omics data to uncover molecular mechanisms underlying photosymbiosis with dinoflagellates.

Un1Cas12f1 and Cas9 gene drive in HSV1: Viruses that 'infect' viruses

This study develops Cas9 and Un1Cas12f1 gene drives in HSV1 to assess gene drive efficacy and resistance, finding Un1Cas12f1 has higher conversion and lower resistance.

Effect of Intermittent Pneumatic Compression on Preventing Deep Vein Thrombosis Using Microfluidic Vein Chip

The paper develops a microfluidic vein chip to simulate IPC effects and identifies optimal parameters for DVT prevention.

Oral Feeding of Nanoplastics reduces Brain function of Mice by Inducing Intestinal IL-1β-producing Macrophages

This study shows that oral nanoplastic exposure in mice leads to gut macrophage activation and IL-1β production, which affects brain function by causing microglial activation and cognitive decline.

The asymmetric ABA response on both sides of root tip is important for tomato root hydrotropism by mediating proton efflux and cell elongation

This study shows that asymmetric ABA response in tomato root tips mediates proton efflux and cell elongation, driving hydrotropic bending toward water.

Non-Invasive Confocal Fluorescence Imaging of Mice Beyond 1700 nm Using Superconducting Nanowire Single-Photon Detectors

This paper develops a non-invasive imaging technique using NIR-IIc light to image deep tissues in mice, achieving imaging depths of ~800 m and visualizing immune structures in lymph nodes.

Enhanced soil quality after forest conversion to vegetable cropland and tea plantation has contrasting effects on soil microbial structure and functions

This study examines how soil quality changes after forest conversion to vegetable cropland and tea plantations, showing contrasting effects on microbial community structure and functions.

Lung Epithelial Cells Can Produce Antibodies Participating In Adaptive Humoral Immune Responses

The paper shows lung epithelial cells can produce TD-Ag-specific antibodies, dependent on CD4+ T cells, challenging the notion that B cells are the sole source of such antibodies.

Genome of the estuarine oyster provides insights into climate impact and adaptive plasticity

The paper analyzes the genome of the estuarine oyster to show how climate history and physical forces shape genomic diversity and adaptive plasticity through gene expansion and regulatory selection.

Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p

This study shows berberine reverses multidrug resistance in Candida albicans by hijacking the Mdr1p efflux pump for drug import, leading to mitochondrial dysfunction and selective cell death.

High-Accuracy Multiplexed SARS-CoV-2 Antibody Assay with Avidity and Saliva Capability on a Nano-Plasmonic Platform

This paper develops a high-accuracy multiplexed SARS-CoV-2 antibody assay using a nano-plasmonic platform, showing high specificity and sensitivity in serum and saliva samples.

Gut bacteria convert cortisol into a distinct hostsignalling molecule

The paper shows gut bacteria convert cortisol into 20-dihydrocortisol, a distinct host signalling molecule that reprograms colonic transcription and activates inflammatory pathways via NR4A3.

The Coevolution of Promoters and Transcription Factors in Animal and Plant Cells

This study shows that promoters and transcription factors coevolve antagonistically in animals and mutually in plants, leading to different transcriptional network transitions.

Immunity-and-Matrix-Regulatory Cells Derived from Human Embryonic Stem Cells Safely and Effectively Treat Mouse Lung Injury and Fibrosis

This study generates and tests human embryonic stem cell-derived immunity-and-matrix-regulatory cells (IMRCs) for treating lung injury and fibrosis in mice, showing efficacy and safety.

Multilocus sequence analysis, a rapid and accurate identification tool for taxonomic classification, evolutionary relationship and population biology of the genus Shewanella.

This paper establishes a multilocus sequence analysis (MLSA) method using six protein-coding genes to classify Shewanella strains, revealing evolutionary relationships and population biology.

Optical Sectioning of Live Mammal with Near-Infrared Light Sheet

This paper develops near-infrared light sheet microscopy to image live mammals, revealing tumor dynamics and PD-L1 receptor distribution at the single-cell level.

Single molecule imaging reveals the concerted release of myosin from regulated thin filaments

The paper uses single molecule imaging to show that myosin detachment from thin filaments occurs in a coordinated, active process during deactivation.