Author

N. M. Samhadaneh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Pironti· 3 shared K. H. Darwin· 3 shared G. Limon· 2 shared D. C. Ekiert· 1 shared G. Bhabha· 1 shared G. Putzel· 1 shared J. Chen· 1 shared J. H. Yoo· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMicrobiology

A. Pironti

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Author profile →

3 papers

Recent·Most cited

Identification of a proteolysis regulator for an essential enzyme in Mycobacterium tuberculosis

S. C. Kahne, J. H. Yoo, J. Chen, K. Nakedi, L. M. Iyer, G. Putzel, N. M. Samhadaneh, A. Pironti, L. Aravind, D. C. Ekiert, G. Bhabha, K. Y. Rhee, K. H. Darwin

The paper identifies CoaX, a pseudokinase, and pantothenate as regulators of proteasomal degradation of the pantothenate synthesis enzyme PanB in M. tuberculosis.

bioRxiv · Mar 29, 2024 · PreprintMicrobiology

Aldehyde accumulation in Mycobacterium tuberculosis with defective proteasomal degradation results in copper sensitivity

G. Limon, N. M. Samhadaneh, A. Pironti, K. H. Darwin

This study shows aldehyde accumulation in M. tuberculosis with defective proteasomal degradation causes copper sensitivity by impairing copper resistance proteins.

bioRxiv · Feb 11, 2023 · PreprintMicrobiology

Aldehyde inactivation of the RicR regulon sensitizes Mycobacterium tuberculosis to copper

G. Limon, N. M. Samhadaneh, A. Pironti, K. H. Darwin

This study shows aldehyde accumulation in M. tuberculosis mutants impairs the RicR regulon, increasing copper sensitivity, and suggests aldehydes may be a host defense mechanism against tuberculosis.

bioRxiv · Sep 30, 2022 · PreprintMicrobiology