Author

N. M. Valenzuela

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Biology Disciplines

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. F. Acevedo· 2 shared J. J. Mack· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersImmunology

A. F. Acevedo

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 3, 2022

The DNA binding protein BCL6 regulates NFκB-controlled endothelial inflammatory gene expression

A. F. Acevedo, J. J. Mack, N. M. Valenzuela

This study shows BCL6 represses NFκB-driven inflammation in cardiac endothelial cells by interacting with NFκB and inhibiting gene expression.

DOI 10.1101/2022.11.03.514942

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 3, 2022

BCL6 regulates the endothelial pro-immunogenic phenotype relevant to organ transplant rejection

A. F. Acevedo, N. M. Valenzuela

This study shows BCL6 regulates endothelial cell responses to IFN-gamma, influencing immunogenicity in transplant rejection.

DOI 10.1101/2022.11.03.514941

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 18, 2021

Endothelial Resolution of Inflammation is Delayed Following JAK-driven but not NFκB-dependent Activation

N. M. Valenzuela

This study compares how JAK-driven and NFκB-dependent inflammation affect endothelial cell function, finding that JAK signaling leads to prolonged pro-adhesive effects while NFκB effects are transient.

DOI 10.1101/2021.06.18.449043

humanbulk RNA-seq

𝕏 PostBluesky