N. Matsumura

This study finds that homologous recombination deficiency (HRD) in cancer cell lines is not associated with sensitivity to platinum agents or PARP inhibitors, contradicting clinical expectations.

This study shows that CXCL13-producing CD4+ T cells induce tertiary lymphoid structures (TLSs) in ovarian cancer, increasing CD8+ T cell and B cell infiltration and improving patient prognosis.

This study identifies frequent PIK3CA mutations in eutopic endometrium of ovarian clear cell carcinoma patients, showing high mutation rates and intratumor heterogeneity.

This study characterizes ovarian cancer spheroid phenotypes, identifies gene expression profiles linked to spheroid formation, and evaluates therapeutic responses of spheroids to various agents.