The Toxin Antitoxin MazEF Drives Staphylococcus aureus Chronic Infection
D. Ma, J. B. Mandell, N. P. Donegan, A. L. Cheung, W. Ma, S. Rothenberger, R. M. Shanks, A. R. Richardson, K. L. Urish
This study shows that the MazEF toxin-antitoxin system in S. aureus inhibits biofilm formation and promotes antibiotic tolerance, facilitating the transition from acute to chronic infection.
bioRxiv · Jun 30, 2019 · PreprintMicrobiology