Author

N. Phadnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 6

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Research Focus:chromatin & epigenetic regulation· 5 Organism:Drosophila· 5 Approach:experimental assay· 4 Assay:DNA methylation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

J. C. Cooper· 4 shared C. J. Leonard· 3 shared A. R. Quinlan· 1 shared B. S. Pedersen· 1 shared C. Leonard· 1 shared C. M. Carey· 1 shared E. F. Joyce· 1 shared J. Bladen· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersEvolutionary Biology

J. C. Cooper

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Author profile →

6 papers

Recent·Most cited

Endless Conflicts: Detecting Molecular Arms Races in Mammalian Genomes

J. C. Cooper, C. J. Leonard, B. S. Pedersen, C. M. Carey, A. R. Quinlan, N. C. Elde, N. Phadnis

The paper detects recurrent positive selection in mammalian genomes across multiple clades, finding shared selective pressures and highlighting PIGR as a gene involved in a long-term molecular arms race.

bioRxiv · Jun 28, 2019 · PreprintEvolutionary Biology

A triple-hybrid cross reveals a new hybrid incompatibility locus between D. melanogaster and D. sechellia

J. C. Cooper, P. Guo, J. Bladen, N. Phadnis

The paper identifies two specific loci responsible for hybrid incompatibility between D. melanogaster and D. sechellia using a triple-hybrid cross and whole genome sequencing.

bioRxiv · Apr 4, 2019 · PreprintEvolutionary Biology

Extensive recombination suppression and chromosome-wide differentiation of a segregation distorter in Drosophila

Z. L. Fuller, S. A. Koury, C. J. Leonard, R. E. Young, K. Ikegami, J. Westlake, S. Richards, S. W. Schaeffer, N. Phadnis

The paper analyzes the evolutionary dynamics of a segregation distorter in Drosophila pseudoobscura, finding that it persists due to suppressed recombination and epistatic selection.

bioRxiv · Dec 21, 2018 · PreprintEvolutionary Biology

Recurrent losses and rapid evolution of the condensin II complex in insects

T. D. King, C. J. Leonard, J. C. Cooper, S. Nguyen, E. F. Joyce, N. Phadnis

The paper investigates the evolution of condensin II complex subunits in insects, finding recurrent losses and positive selection across species.

bioRxiv · Nov 16, 2018Evolutionary Biology

The role of chromosomal inversions in speciation

Z. Fuller, C. Leonard, R. Young, S. Schaeffer, N. Phadnis

This study reconstructs the evolutionary history of chromosomal inversions in D. persimilis and D. pseudoobscura, showing that inversions segregate before speciation and contribute to hybrid incompatibilities.

bioRxiv · Nov 24, 2017Evolutionary Biology

Parallel evolution of sperm hyper-activation Ca2+ channels

J. C. Cooper, N. Phadnis

The paper examines the molecular evolution of sperm hyper-activation channels in primates and Drosophila, finding rapid positive selection in CatSper and parallel adaptive evolution in pkd2.

bioRxiv · Apr 17, 2017Evolutionary Biology