Tenascin-C activation of lung fibroblasts in a 3D synthetic lung extracellular matrix mimic
A. N. Kundu, C. E. Dougan, S. Mahmoud, A. Kilic, A. Panagiotou, N. Irakoze, N. Richbourg, S. R. Peyton
This study develops a synthetic lung ECM hydrogel to study fibroblast activation, showing that tenascin-C and TGF-β1 activate fibroblasts in the hydrogel similar to in vivo responses.
bioRxiv · Feb 24, 2023Bioengineering