Author

N. S. Spoelstra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

J. K. Richer· 2 shared A. R. Raimondi· 1 shared F. L. Couto· 1 shared H. T. Lind· 1 shared J. L. Christenson· 1 shared J. T. Roberts· 1 shared K. I. O'Neill· 1 shared L. Rocha-Viegas· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. K. Richer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

RUNX1 is regulated by androgen receptor to promote cancer stem markers and chemotherapy resistance in triple negative breast cancer.

N. B. Fernandez, S. M. Sosa, J. T. Roberts, M. S. Recouvreux, L. Rocha-Viegas, J. L. Christenson, N. S. Spoelstra, F. L. Couto, A. R. Raimondi, J. K. Richer, N. Rubinstein

This study shows that RUNX1 is regulated by androgen receptor in TNBC, promoting cancer stem cell markers and chemotherapy resistance.

bioRxiv · Nov 12, 2022Cancer Biology

NPC1 confers metabolic flexibility in Triple Negative Breast Cancer

K. I. O'Neill, L.-W. Kuo, M. M. Williams, H. T. Lind, L. S. Crump, N. G. Hammond, N. S. Spoelstra, M. C. Caino, J. K. Richer

This study identifies NPC1 as a key driver of metabolic flexibility and aggressiveness in TNBC, showing its role in cholesterol homeostasis and therapeutic vulnerability.

bioRxiv · May 5, 2022Cancer Biology