Author

J. T. Roberts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. B. Coley· 2 shared B. C. Watters· 2 shared C. H. McInnis· 2 shared C. L. Brown· 2 shared D. Houserova· 2 shared G. M. Borchert· 2 shared J. D. DeMeis· 2 shared J. Huang· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. B. Coley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

RUNX1 is regulated by androgen receptor to promote cancer stem markers and chemotherapy resistance in triple negative breast cancer.

N. B. Fernandez, S. M. Sosa, J. T. Roberts, M. S. Recouvreux, L. Rocha-Viegas, J. L. Christenson, N. S. Spoelstra, F. L. Couto, A. R. Raimondi, J. K. Richer, N. Rubinstein

This study shows that RUNX1 is regulated by androgen receptor in TNBC, promoting cancer stem cell markers and chemotherapy resistance.

bioRxiv · Nov 12, 2022Cancer Biology

MicroRNA-like snoRNA-derived RNAs (sdRNAs) promote castration resistant prostate cancer

A. B. Coley, A. N. Stahly, M. V. Kasukurthi, A. A. Barchie, S. B. Hutcheson, D. Houserova, Y. Huang, B. C. Watters, V. M. King, M. A. Dean, J. T. Roberts, J. D. DeMeis, C. H. McInnis, N. L. Godang, R. M. Wright, , G. M. Borchert

This study identifies two snoRNA-derived fragments, sdRNA-D19b and sdRNA-A24, that promote castration-resistant prostate cancer by downregulating tumor suppressors and conferring drug resistance.

bioRxiv · Dec 17, 2021Cancer Biology

Salmonella Outer Membrane Vesicles contain tRNA Fragments (tRFs) that Inhibit Bacteriophage P22 infection

D. Houserova, Y. Huang, M. V. Kasukurthi, B. C. Watters, F. F. Khan, R. V. Mehta, N. Y. Chaudhary, J. T. Roberts, J. D. DeMeis, T. K. Hobbs, K. R. Ghee, C. H. McInnis, N. P. Johns, A. J. Kegler, A. B. Coley, , G. M. Borchert

This study identifies tRNA fragments (tRFs) in Salmonella OMVs that inhibit bacteriophage P22 infection, showing their role in antiviral defense.

bioRxiv · Nov 9, 2021 · PreprintMicrobiology

RNA matchmaking remodels lncRNA structure and promotes PRC2 activity

M. M. Balas, E. W. Hartwick, C. Barrington, J. T. Roberts, S. K. Wu, R. Bettcher, A. M. Griffin, J. S. Kieft, A. M. Johnson

The paper shows that RNA matchmaking between HOTAIR and target gene RNAs relieves PRC2 inhibition, promoting its activity through structural changes and hnRNP B1-mediated interactions.

bioRxiv · Apr 13, 2020 · PreprintBiochemistry