Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
L. E. Miller-Vedam, B. Bräuning, K. D. Popova, N. T. Schirle Oakdale, J. L. Bonnar, J. R. Prabu, E. A. Boydston, N. Sevillano, M. J. Shurtleff, R. M. Stroud, C. S. Craik, B. Schulman, A. Frost, J. S. Weissman
The paper reveals the structural and mechanistic basis of EMC's role in biogenesis of distinct transmembrane proteins through cryo-EM structures and functional studies.
bioRxiv · Sep 2, 2020Biophysics